Stress affects men & women, but how they experience it can differ. Although stress is a natural response to difficult situations, it can have negative long-term consequences for men's well-being if it becomes chronic or prolonged. In this guide, we explore the effects of stress on men's health, including their physical and psychological symptoms. We also provide tips on how men can manage stress effectively. Finally, we will discuss the potential benefits of combining sertraline and Viagra to improve both the psychological and sexual effects of stress.

What Is Stress?

Stress is an inevitable part of life. It’s a natural response of the body to a challenge or demand that can come from various events or thoughts that make you feel frustrated, angry, or nervous. Besides, it’s a response to challenging situations, such as work deadlines, relationship problems, financial struggles, or health issues. However, when stress becomes chronic or prolonged, it can have negative effects on our mental and physical health.

Here are two primary forms of stress:

acute stress is short-term stress that subsides quickly. It can be felt in situations such as sudden braking, an argument with a partner, or skiing down a steep slope. Acute stress can help individuals deal with hazardous circumstances and is also experienced during new or thrilling experiences. It’s common for everyone to experience acute stress at some point;
chronic stress, which lasts for an extended period. It may arise due to factors such as financial problems, an unhappy marriage, or workplace issues. Any stress that persists for weeks or months is classified as chronic stress. Individuals may become accustomed to chronic stress to the point where they aren’t aware of its detrimental effects.

You might also feel chronic stress if your day-to-day life is challenging.

Stress in Men vs. Women: Common and Distinctive Features

Stress manifests differently in men and women, influenced by various factors such as biology, immunity, sex hormones, and fight-or-flight responses. Research suggests the following general differences [1]:

stress response: Men tend to exhibit a greater stress response than women due to the activation of the hypothalamic-pituitary-adrenal axis and sympathetic nervous system. This puts them at higher risk for increased aggression, cardiovascular disease, and decreased immune functioning;
brain activation: Stress activates different brain areas in men and women. Men show a stronger stress response and higher levels of cortisol in their saliva when exposed to the same stressors;
stress-coping strategies: Men are more likely to exhibit a fight-or-flight response, while women tend to display tend-and-befriend behaviors. This difference in response patterns makes men more susceptible to high levels of stress in certain situations compared to women;
impact on chronic pain: Testosterone plays a role in mitigating feelings of pain, but stress can decrease testosterone levels and increase cortisol, thereby intensifying pain sensations. Indeed, chronic pain may affect men differently due to the interplay between testosterone, stress, and pain.

Individual factors such as culture, religious beliefs, upbringing, childhood trauma experiences, and genetic factors also contribute to the processing of stress in men and women.

Symptoms of Stress in Men: Physical, Psychological and Behavioral Signs

In men, stress manifests as physical, psychological, and behavioral symptoms. Here are some common signs of stress in men [2]:

Physical symptoms: 

headaches and migraines;
muscle tension and pain;
digestive problems (stomach pain, constipation, and diarrhea);
high blood pressure;
neck, back, chest pain, and rapid heartbeat;
insomnia or sleep disturbances;
fatigue and exhaustion;
trouble achieving or maintaining an erection. 

Psychological symptoms: 

anxiety and irritability;
anger and hostility;
depression and mood swings;
difficulty concentrating and making decisions;
feelings of overwhelm and loss of control;
lack of motivation and interest in activities;
forgetfulness and memory problems;
racing thoughts or inability to quiet the mind. 

Behavioral symptoms:

overeating or undereating;
increased use of alcohol or drugs;
social withdrawal and isolation;
impulsive behaviors, e.g., aggression or risk-taking such as reckless driving;
procrastination and neglecting responsibilities, such as work or family obligations;
decreased performance at work or school;
avoiding activities that used to be enjoyable.

Not everyone will experience the same symptoms, and some people may not have any symptoms at all. Seeking support and developing healthy coping strategies can help reduce stress and improve overall well-being.

What Are the Longterm Effects of Stress? 

Men, in particular, may be vulnerable to certain health issues that can arise from chronic stress. The physical, psychological, and behavioral symptoms of stress can be severe and negatively impact men's health. Common consequences of stress on men's health include:

Cardiovascular Disease

When stressed, the body releases stress hormones, such as adrenaline and cortisol, which can increase heart rate and blood pressure, causing the heart to work harder. Over time, this can damage blood vessels and lead to a buildup of plaque in the arteries, a condition known as atherosclerosis. This, in turn, can increase the risk of heart attack and stroke. Additionally, stress can lead to unhealthy behaviors, such as overeating, smoking, and physical inactivity, which can also contribute to the development of cardiovascular disease.

Chronic Gastrointestinal Problems

Chronic stress can also contribute to gastrointestinal problems, such as irritable bowel syndrome, inflammatory bowel disease, and peptic ulcers. When the body is under stress, the brain sends signals to the digestive system to slow or shut down digestion, which can lead to digestive problems. Additionally, stress can reduce blood flow and alter gut microbiota. These changes can exacerbate gastrointestinal issues and lead to chronic problems over time. Stress may also affect eating habits, leading to overeating or undereating, which can further impact digestive health.

Promotes Cancer Development

Chronic stress may lead to changes in the body's hormone levels, inflammation, and oxidative stress, which could potentially contribute to the development and progression of cancer [3]. Additionally, stress may affect immune function and increase the risk of cancer by impairing the body's ability to fight off cancerous cells. Stress can also lead to unhealthy behaviors such as smoking, drinking alcohol, and poor diet, which are known risk factors for prostate cancer. Extreme stress can have an accumulative impact on the body’s physiology, permitting prostate cancer to take root & grow [4]. Therefore, while stress alone may not directly cause prostate cancer, it may increase the risk of developing the disease through its impact on the immune system and unhealthy behaviors.

Male Infertility

Chronic stress can lead to the overproduction of cortisol, a hormone that helps the body cope with stress. However, high levels of cortisol can suppress the production of other hormones, such as testosterone, which is essential for sperm production. Stress also causes changes in sperm quality and quantity, such as a decrease in sperm count, motility, and morphology. Chronic stress can also lead to a decrease in sexual desire and performance, which can affect fertility. Additionally, stress can lead to unhealthy lifestyle choices, such as smoking and alcohol consumption, which can further impact male fertility.

Erectile Dysfunction

Erectile dysfunction (ED) is the inability to achieve or maintain an erection firm enough for sexual intercourse. Stress is a common cause of ED in men. Stress affects the body's ability to produce & regulate hormones, inducing blood vessels to constrict, and reducing blood flow to the penis, making it harder to achieve and maintain an erection.

When a man is under stress, the body releases the hormone cortisol, which can interfere with the production of testosterone and other hormones needed for sexual function. High levels of cortisol can also cause blood vessels to constrict, which reduces blood flow to the penis.

Additionally, stress can cause psychological factors which can further contribute to ED. Stress can also lead to unhealthy coping mechanisms such as smoking, drinking alcohol, or using drugs, which can worsen ED. Chronic stress can lead to fatigue and exhaustion, making it difficult for men to engage in sexual activity.

Impressively, a combination of Sertraline and Viagra may help improve the psychological state, sexual function, and overall health of men. Sertraline is an antidepressant med that can help reduce symptoms of anxiety and depression that may contribute to stress. Viagra, on the other hand, is a medication used to treat ED. The combination of these two drugs improves sexual function in men who have both ED and psychological distress related to stress. However, this combination therapy should only be taken under the guidance of a doctor.

Stress Management: Healthy Ways to Cope with Stress

When it comes to managing stress and improving their overall health and well-being, there are a variety of healthy coping mechanisms that can be effective. Here are some tips:

Lifestyle Changes

Identify the sources of stress in your life and try to avoid or minimize them. For example, if you find that a certain activity or person consistently causes stress, consider limiting your exposure to it or finding alternative solutions.

Set realistic goals and prioritize tasks to reduce feelings of overwhelm. This can help you focus on the most important things and avoid taking on too much at once. Additionally, learning to say "no" can be empowering and help you to maintain boundaries and avoid over-commitment.

Making time for enjoyable activities and hobbies can provide a much-needed break from stress and help you recharge and refocus, as well as effectively manage stress and improve your overall quality of life.

Exercise Regularly

Exercise helps to reduce tension, improve mood, increase energy levels, and promote better sleep. It can also improve cardiovascular health, lower blood pressure, and reduce the risk of chronic diseases. To reap these benefits, aim for at least 30 minutes of moderate-intensity exercise most days of the week. Choose an activity that you enjoy, such as running, swimming, or playing sports, as this can help you stick to a regular exercise routine.

Eat a Balanced Diet

Eating a balanced diet is essential for maintaining good health and reducing the negative effects of stress. Consuming a diet rich in fruits, vegetables, whole grains, and lean proteins provides the body with the nutrients it needs to function optimally. On the other hand, consuming excessive amounts of caffeine, alcohol, and processed foods can exacerbate stress and lead to negative health consequences. Fruits and vegetables contain antioxidants that help reduce inflammation in the body and improve immune function.

Get Enough Sleep

Adequate sleep (7-9 hours of sleep per night) is essential for managing stress effectively. It allows the body and mind to rest, recover, and regulate stress hormones. Quality sleep enhances emotional resilience, cognitive functioning, and the ability to handle stress. Establishing a regular sleep schedule and creating a conducive sleep environment is important for getting enough sleep and improving overall well-being.

Find Support

Having a support system is crucial in managing stress. Whether it's reaching out to friends or family members or joining a support group, having someone to talk to can help alleviate stress. For those who need more help, seeking counseling or therapy can be an effective way to address stress-related issues and develop coping strategies. Speak with a doctor if stress is interfering with daily life.

Oral Medications

While oral meds can help manage stress and improve sexual function, they should only be taken under the guidance and supervision of a healthcare professional. Additionally, medication should be used in conjunction with other stress management techniques, such as exercise and counseling, for optimal results.


In conclusion, stress can have a significant impact on men's physical, emotional, and psychological health. It can lead to a range of adverse long-term effects, including cardiovascular disease, gastrointestinal problems, prostate cancer, male infertility, and ED. However, there are various healthy ways to cope with stress, such as lifestyle changes, regular exercise, a balanced diet, adequate sleep, finding support, and oral medications. Men need to recognize the signs of stress and take steps to manage it to improve their overall health and well-being. With the right approach, stress can be effectively managed, and men can lead healthy and fulfilling life.


1. How to Recognize Stress Symptoms in Men. By Jerry Kennard. Updated: April 26, 2021. Retrieved: May 16, 2023. Medically reviewed by David Susman.
2. How to Tell When a Man Is Stressed. By Adrienne Santos-Longhurst. Medically reviewed by Dillon Browne. Updated: August 22, 2018.
3. Chronic Stress Promotes Cancer Development. By Shirui Dai, Yongzhen Mo, Yumin Wang, et al. Published: August 2020.
4. Stress and Cancer. Published: September 5, 2018.